MOTS c for Weight Loss
MOTS c for weight loss is a search about the most interesting idea in metabolic peptides. MOTS-c is a sixteen amino acid peptide. Your mitochondria carry the code for it. They are the parts of the cell that make energy. You will need to create a free account with the vendor below to be able to order.
Ordering is easy once you have created your account.

When will I get my order?
- Depending on the vendor your order from, you will receive your peptides within 7 business days. Here is shipping speed by vendor:
- Amino Club: 3 ot 5 Business Days
- EZ Peptides: 5 to 7 Business Days
- Ascension: 5 to 7 Business Days

What Is MOTS-c?
MOTS-c was discovered in 2015. Your muscles release it during exercise, and it is tied to how they burn fuel. The landmark Cell Metabolism paper showed it stopped mice from getting fat on a rich diet. It kept them insulin sensitive too. It is still a research compound everywhere.

Does MOTS-c Work for Weight Loss?
In mice, the data is striking. Animals on a rich diet given MOTS-c stayed lean and insulin sensitive. In humans, the closest evidence is indirect. A drug version called CB4211 finished a Phase 1 trial in 2021. The liver fat and weight numbers looked good, but they were announced and never published. The table below is a brief summary of the research.

| Finding | Model |
|---|---|
| Prevented diet-induced obesity | Mouse study, Cell Metabolism (2015) |
| Muscle and fat metabolism effects | Reviewed across rodent studies (2016) |
| CB4211 analog Phase 1 topline | Company announcement, unpublished (2021) |
| Human MOTS-c weight-loss trials | None published |
What this evidence does not cover
No human trial of MOTS-c itself has ever been published, and nothing here is FDA approved. Mouse metabolism is not human metabolism. A company press release is not a paper. Research vials are not weight-loss products, and a batch-matched third-party COA is still the minimum standard.
Primary sources
- MOTS-c promotes metabolic homeostasis and reduces obesity in mice — Cell Metabolism, 2015
- MOTS-c, a mitochondrial-derived peptide regulating muscle and fat metabolism — 2016 review
- CB4211 Phase 1 topline results announcement — CohBar, 2021
What Does MOTS-c Cost?
MOTS-c runs $40 to $70 for a 10mg vial, or several dollars per mg. That is mid-range for research peptides. Demand has climbed since the mouse data spread.
Prices well below that range usually mean skipped testing or short-filled vials. Metabolic hype travels fast, and quality control does not.

Ready to order MOTS-c?
Research use only. Third-party tested, shipped in 3 to 5 business days.