PT-141 Peptide for Men

PT 141 peptide for men is available online as a research compound. Unlike other treatments (such as those that affect blood flow) this treatment acts upon the brain and/or nervous system. It first gained attention during research for having the unexpected effect of spontaneous erections with some of the male participants.

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PT-141 Peptide for Men

What is PT-141?

PT-141, also called bremelanotide, was spun out of melanotan research when trial volunteers reported an unexpected effect of spontaneous erections. In 2019 the FDA approved PT-141 (bremelanotide) under the trade name Vyleesi; however, this approval was for only premenopausal women. As far as men are concerned, it continues to be used as a research compound and one of the most frequently purchased compounds available.


Does PT-141 work in men?

The male data is actual however it is also dated. In 2004, a randomized double blind placebo controlled trial of intranasal PT-141 assessed the effect of intranasal PT-141 on erectile response in both healthy men and men who experienced mild to moderate Erectile Dysfunction (ED). In 2005, a subsequent study found that there was an increased response to PT-141 when it was co-administered with Sildenafil. The male program was eventually closed down. A brief review of the research is provided in the table below.

FindingModel
Erectile responses measuredDouble-blind male trial (2004)
Enhanced response with sildenafilMale co-administration study (2005)
FDA approval as VyleesiPremenopausal women only (2019)
Male ED development programDiscontinued

What this evidence does not cover

PT-141 was never specifically approved for men; however, PT-141 peptide for men is commonly discussed through online forums and social media. Research trials showed increased blood pressure, flushing and nausea – all reasons why the male program ended. Research vials are not pharmacy Vyleesi and any product sold as a final performance product is considered grey market. When purchasing this compound you should require a batch-matched third party COA as your minimum standard.

Primary sources


What does PT-141 cost per mg?

PT-141 generally runs $40 to $60 for a 10mg vial, about $5 per mg. Ascension Peptides currently lists 10mg at $49 with batch-specific COAs from independent labs.


When will I get my order?

  • Depending on the vendor you order from, shipping typically takes:
    • Amino Club: 3 to 5 Business Days
    • EZ Peptides: 5 to 7 Business Days
    • Ascension: Same-day dispatch on orders before 2pm CST
when will I get my order

Ready to order PT-141?

Research use only. Third-party tested, fast dispatch from US stock.